Overall IVF is a safe treatment. A condition known as ovarian hyper stimulation may occur, whereby a woman’s ovaries become over-stimulated and enlarged, and at the same time fluid accumulates in her abdomen- endangering life. However with present day antagonist, this regime of risk is virtually eliminated. Multiple pregnancies, which can be avoided by a single Embryo Transfer and the relation of IVF and future ovarian malignancy is unfounded and unproven.